Skip to main content
Publications | Persons | Institutes | Projects
[ report an error in this record ]basket (0): add | show Print this page

A pilot study of the cognitive and psychological correlates of chronic ciguatera poisoning
Arena, P.; Levin, B.; Fleming, L.E.; Friedman, M.A.; Blythe, D. (2004). A pilot study of the cognitive and psychological correlates of chronic ciguatera poisoning. Harmful Algae 3(1): 51-60. dx.doi.org/10.1016/j.hal.2003.08.006
In: Harmful Algae. Elsevier: Tokyo; Oxford; New York; London; Amsterdam; Shannon; Paris. ISSN 1568-9883; e-ISSN 1878-1470, more
Peer reviewed article  

Available in  Authors 

Keyword
    Marine/Coastal
Author keywords
    Neuropsychologic effects; Ciguatera fish poisoning; Mannitol; Harmful algal blooms; Marine toxins; Ciguatoxin

Authors  Top 
  • Arena, P.
  • Levin, B.
  • Fleming, L.E., more
  • Friedman, M.A.
  • Blythe, D.

Abstract
    Ciguatera fish poisoning is the most frequently reported seafood-toxin illness in the world, caused by the consumption of coral reef fishes contaminated with a group of natural toxins produced by minute phytoplankton (dinoflagellates). These toxins are potent and cause both acute and chronic neurologic disease in humans.Although ciguatera fish poisoning is associated with established neurotoxins in animal models, and with known peripheral nervous system effects in humans, this pilot study was the first to explore possible central nervous system effects associated with chronic ciguatera poisoning in humans. In a matched cohort design, 12 cases and 12 their age and gender matched friend controls underwent a battery of neuropsychological tests. The results indicated that although their scores on objective neuropsychological tests did not differ significantly from matched controls, persons with ciguatera reported a higher degree of toxicity-related symptomatology and endorsed significantly more depressive symptomatology than controls. Future research should explore larger numbers of persons with both acute and chronic ciguatera, with and without mannitol treatment.

All data in the Integrated Marine Information System (IMIS) is subject to the VLIZ privacy policy Top | Authors