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Live-food mediated drug delivery as a tool for disease treatment in larviculture: 2. A case study with European seabass
Chair, M.; Romdhane, M.S.; Dehasque, M.; Nelis, H.; De Leenheer, A.P.; Sorgeloos, P. (1991). Live-food mediated drug delivery as a tool for disease treatment in larviculture: 2. A case study with European seabass, in: Lavens, P. et al. Larvi '91. Short communications and abstracts of contributions presented at the international Symposium on Fish and Crustacean Larviculture. Gent, Belgium, August 27-30, 1991. Special Publication European Aquaculture Society, 15: pp. 412-414
In: Lavens, P. et al. (1991). Larvi '91: Short communications and abstracts of contributions presented at the international Symposium on Fish and Crustacean Larviculture. Gent, Belgium, August 27-30, 1991. Special Publication European Aquaculture Society, 15. European Aquaculture Society: Gent. ISBN 90-71625-09-5. 427 pp., more
In: Special Publication European Aquaculture Society. European Aquaculture Society: Bredene. ISSN 0774-0689, more
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Keywords
    Additives > Food additives
    Aquaculture techniques
    Aquatic organisms > Food organisms
    Control > Disease control
    Cultures > Fish culture
    Developmental stages > Larvae > Fish larvae
    Drugs > Antibiotics
    Dicentrarchus labrax (Linnaeus, 1758) [WoRMS]
    Marine/Coastal
Authors  Top 
  • Chair, M.
  • Romdhane, M.S.
  • Dehasque, M., more
  • Nelis, H.
  • De Leenheer, A.P.
  • Sorgeloos, P., more
Abstract
    The purpose of this study is to investigate the possibility of oral delivery of the antibiotics Trimethoprim (TMP) and Sulfamethoxazole (SMX) to marine fish larvae through incorporation of these antibiotics into the live food organism Artemia. SMX and TMP were selected for their wide range action against gram negative pathogenic bacteria and because of their limited solubility in seawater. Ormetoprim-Sulfadimethoxine (brand name Romet-30) is a new combination of a similar antimicrobial drug used in aquaculture. Diseased penaeid larvae fed Romet-30 through the food chain exhibited greater survival than the untreated ones. In an earlier study Verpraet have described a technique for bioencapsulating high doses of more than 500 mu g TMP + SMX per gram dry weight (DW) Artemia nauplii. In this study we have used 2-month-old European seabass (Dicentrarchus labrax) larvae that were fed with TMP + SMX - bioencapsulated Artemia nauplii.
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