one publication added to basket [100241] | Induction of micronuclei and other nuclear abnormalities in mussels exposed to bisphenol A, diallyl phthalate and tetrabromodiphenyl ether-47
Baršienė, J.; Šyvokienė, J.; Bjornstad, A. (2006). Induction of micronuclei and other nuclear abnormalities in mussels exposed to bisphenol A, diallyl phthalate and tetrabromodiphenyl ether-47. Aquat. Toxicol. 78(Supplement 1): S105-S108. https://dx.doi.org/10.1016/j.aquatox.2006.02.023
In: Aquatic Toxicology. Elsevier Science: Tokyo; New York; London; Amsterdam. ISSN 0166-445X; e-ISSN 1879-1514, more
Also appears in:Pampanin, D.M.; Anderson, O.K.; Viarengo, A. (Ed.) (2006). The Stavanger Workshop: Biological Effects of Environmental Pollution (BEEP) in marine coastal ecosystem: the Stavanger mesocosm exposure studies. Aquatic Toxicology, Special Issue 78(Suppl. 1). Elsevier: The Netherlands. S1-S128 pp., more
| |
Keyword |
|
Author keywords |
micronuclei; mussells; bisphenol A; diallyl phthalate;tetrabromodiphenyl ether-47 |
Authors | | Top |
- Baršienė, J.
- Šyvokienė, J.
- Bjornstad, A.
|
|
|
Abstract |
Analysis of micronuclei, nuclear buds, bi-polynucleated and fragmented-apoptotic cells was performed in gills of blue mussels exposed for 3 weeks to sublethal concentrations of bisphenol A, diallyl phthalate (for the both nominal concentration 50 ppb) and to tetrabromodiphenyl ether-47 (nominal concentration 5 ppb). Fourteen specimens from each treatment and control group were used for the analysis. Our results demonstrated a significant increase in micronuclei frequency after the treatment with bisphenol A (P = 0.0243), diallyl phthalate (P = 0.0005) and tetrabromodiphenyl ether-47 (P < 0.0001; Mann–Whitney U-test). Induction of bi-nucleated (P = 0.0028), fragmented-apoptotic (P = 0.0004) cells and nuclear buds (P = 0.0101) was found in mussels exposed to tetrabromodiphenyl ether-47 while treatment with diallyl phthalate increased the level of fragmented-apoptotic cells (P = 0.0283). Bisphenol A was the only agent that resulted only in induction of micronuclei but not any other kind of nuclear injuries. |
|