| one publication added to basket [222417] | Genital warts in Burmeister's porpoises: characterization of Phocoena spinipinnis papillomavirus type 1 (PsPV-1) and evidence for a second, distantly related PsPV
Van Bressem, M.-F.; Cassonnet, P.; Rector, A.; Desaintes, C.; Van Waerebeek, K.; Alfaro-Shigueto, J.; Van Ranst, M.; Orth, G. (2007). Genital warts in Burmeister's porpoises: characterization of Phocoena spinipinnis papillomavirus type 1 (PsPV-1) and evidence for a second, distantly related PsPV. J. Gen. Virol. 88(7): 1928-1933. http://dx.doi.org/10.1099/vir.0.82694-0
In: Journal of General Virology. Cambridge University Press: London. ISSN 0022-1317; e-ISSN 1465-2099, more
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| Authors | | Top |
- Van Bressem, M.-F.
- Cassonnet, P.
- Rector, A., more
- Desaintes, C.
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- Van Waerebeek, K., more
- Alfaro-Shigueto, J.
- Van Ranst, M., more
- Orth, G.
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| Abstract |
We identified sequences from two distantly related papillomaviruses in genital warts from two Burmeister's porpoises, including a PV antigen-positive specimen, and characterized Phocoena spinipinnis papillomavirus type 1 (PsPV-1). The PsPV-1 genome comprises 7879 nt and presents unusual features. It lacks an E7, an E8 and a bona fide E5 open reading frame (ORF) and has a large E6 ORF. PsPV-1 L1 ORF showed the highest percentage of nucleotide identity (54–55?%) with human papillomavirus type 5, bovine papillomavirus type 3 (BPV-3) and Tursiops truncatus papillomavirus type 2 (TtPV-2). This warrants the classification of PsPV-1 as the prototype of the genus Omikronpapillomavirus. PsPV-1 clustered with TtPV-2 in the E6 and E1E2 phylogenetic trees and with TtPV-2 and BPV-3 in the L2L1 tree. This supports the hypothesis that PV evolution may not be monophyletic across all genes. |
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