one publication added to basket [257838] | Synthesis and antitumor evaluation of analogues of the marine pyrroloiminoquinone tsitsikammamines
Rives, A.; Le Calvé, B.; Delaine, T.; Legentil, L.; Kiss, R.; Delfourne, E. (2010). Synthesis and antitumor evaluation of analogues of the marine pyrroloiminoquinone tsitsikammamines. Eur. J. Med. Chem. 45(1): 343-351. http://dx.doi.org/10.1016/j.ejmech.2009.10.019
In: European Journal of Medicinal Chemistry. Elsevier: Amsterdam. ISSN 0223-5234; e-ISSN 1768-3254, more
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Keyword |
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Author keywords |
Marine alkaloid; Pyrroloiminoquinone; Tsitsikammamine; Antitumoractivity |
Authors | | Top |
- Rives, A.
- Le Calvé, B.
- Delaine, T.
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- Legentil, L.
- Kiss, R., more
- Delfourne, E.
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Abstract |
Two series of analogues of the marine pyrroloiminoquinone alkaloids tsitsikammamine have been synthesized on the basis of a Michael addition between 2'-amino-1-(4-methoxyphenyl)-ethanol and two indolediones. All the compounds were evaluated in vitro for anti proliferative activity against distinct cancer cell lines. |
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