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Preliminary study of oxidative stress biomarkers and trace elements in North Sea harbour seals
Gismondi, E.; Daneels, L.; Damseaux, F.; Lehnert, K.; Siebert, U.; Das, K. (2021). Preliminary study of oxidative stress biomarkers and trace elements in North Sea harbour seals. Mar. Pollut. Bull. 163: 111905. https://hdl.handle.net/10.1016/j.marpolbul.2020.111905
In: Marine Pollution Bulletin. Macmillan: London. ISSN 0025-326X; e-ISSN 1879-3363, more
Peer reviewed article  

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Keywords
    Phoca vitulina Linnaeus, 1758 [WoRMS]
    Marine/Coastal
Author keywords
    Oxidative stress biomarkers; Harbour seal; Phoca vitulina; Trace elements; Red blood cells; Serum

Authors  Top 
  • Lehnert, K.
  • Siebert, U.
  • Das, K., more

Abstract
    This preliminary study investigated the potential correlations between trace elements (mercury, zinc, cadmium, copper, selenium, lead, nickel, chromium, lithium and vanadium) concentrations, measured in red blood cells, and oxidative stress biomarkers (total thiols, total glutathione, total and selenium-dependent glutathione peroxidases, triglycerides, malondialdehyde) assessed in the respective serum, in males and females P. vitulina, sampled in the Wadden Sea in spring and autumn 2015.

    Only concentrations of total mercury and zinc showed significant differences by sex, and only lipid peroxidation was different by season. Moreover, significant positive and negative correlations were observed between biomarkers (triglycerides, thiols, malondialdehyde, glutathione) and trace element concentrations (copper, lead, mercury, nickel, zinc). These findings suggest that the studied biomarkers could be useful for the assessment of oxidative stress in harbour seals exposed to trace elements, but further research with larger sample sizes is needed to better understand their specific associations.


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