| one publication added to basket [77358] | Short term fasting does not aggravate immunosuppression in harbour seals (Phoca vitulina) with high body burdens of organochlorines
de Swart, R.L.; Ross, P.S.; Timmerman, H.H.; Hijman, W.C.; De Ruiter, E.; Liem, A.K.D.; Brouwer, A.; van Loveren, H.; Reijnders, P.J.H.; Vos, J.G.; Osterhaus, A.D.M.E. (1995). Short term fasting does not aggravate immunosuppression in harbour seals (Phoca vitulina) with high body burdens of organochlorines, in: de Swart, R.L. Impaired immunity in seals exposed to bioaccumulated environmental contaminants = Immuunsuppressie in zeehonden blootgesteld aan in de voedselketen geaccumuleerde milieuvervuilende stoffen. pp. 95-110
In: de Swart, R.L. (1995). Impaired immunity in seals exposed to bioaccumulated environmental contaminants = Immuunsuppressie in zeehonden blootgesteld aan in de voedselketen geaccumuleerde milieuvervuilende stoffen. PhD Thesis. Erasmus Universiteit Rotterdam: Rotterdam. ISBN 90-9008419-3. 140 pp., more
Related to:de Swart, R.L.; Ross, P.S.; Timmerman, H.H.; Hijman, W.C.; De Ruiter, E.; Liem, A.K.D.; Brouwer, A.; van Loveren, H.; Reijnders, P.J.H.; Vos, J.G.; Osterhaus, A.D.M.E. (1995). Short term fasting does not aggravate immunosuppression in harbour seals ( Phoca vitulina) with high body burdens of organochlorines. Chemosphere 31(10): 4289-4306, more
|
| Keywords |
Phoca vitulina Linnaeus, 1758 [WoRMS]
Marine/Coastal |
| Authors | | Top |
- de Swart, R.L.
- Ross, P.S.
- Timmerman, H.H.
- Hijman, W.C.
|
- De Ruiter, E.
- Liem, A.K.D.
- Brouwer, A.
- van Loveren, H.
|
- Reijnders, P.J.H., more
- Vos, J.G.
- Osterhaus, A.D.M.E.
|
| Abstract |
Two groups of 11 harbour seals (Phoca vitulina) with different body burdens of organochlorines were subjected to an experimental 15-day fasting period, during which they lost an average 16.5% of their body weights. Blood levels of the most persistent organochlorines showed an approximate twofold increase, while levels of aryl hydrocarbon receptor-binding organochlorines remained largely unaffected. Few differences in immunological parameters were observed between the two dietary groups. Numbers of circulating lymphocytes dropped to about 65% of the initial values and NK cell activity showed a slight increase in both groups. Mitogen- and antigen-induced lymphoproliferative responses of the Baltic group of seals remained within normal ranges. These results suggest that relatively short-term fasting periods do not present an additional immunotoxicological risk to seals with high body burdens of organochlorines. |
|
