Asymmetric synthesis of cyclo-archaeol and ß-glucosyl cyclo-archaeol
Ferrer, C.; Fodran, P.; Barroso, S.; Gibson, R.; Hopmans, E.C.; Sinninghe Damsté, J.S.; Schouten, S.; Minnaard, A.J. (2013). Asymmetric synthesis of cyclo-archaeol and ß-glucosyl cyclo-archaeol. Org. Biomol. Chem. 11(15): 2482-2492. dx.doi.org/10.1039/c3ob27277j
In: Organic & Biomolecular Chemistry. Royal Society of Chemistry: Cambridge. ISSN 1477-0520; e-ISSN 1477-0539, meer
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| Auteurs | | Top |
- Ferrer, C.
- Fodran, P.
- Barroso, S.
- Gibson, R., meer
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- Hopmans, E.C., meer
- Sinninghe Damsté, J.S., meer
- Schouten, S., meer
- Minnaard, A.J.
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| Abstract |
An efficient asymmetric synthesis of cyclo-archaeol and beta-glucosyl cyclo-archaeol is presented employing catalytic asymmetric conjugate addition and catalytic epoxide ring opening as the key steps. Their occurrence in deep sea hydrothermal vents has been confirmed by chromatographic comparison with natural samples. |
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